Detalhe da pesquisa
1.
USP7 substrates identified by proteomics analysis reveal the specificity of USP7.
Genes Dev
; 36(17-18): 1016-1030, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302555
2.
A gene regulatory network approach harmonizes genetic and epigenetic signals and reveals repurposable drug candidates for multiple sclerosis.
Hum Mol Genet
; 32(6): 998-1009, 2023 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36282535
3.
Genetic Deletion of Galectin-3 Inhibits Pancreatic Cancer Progression and Enhances the Efficacy of Immunotherapy.
Gastroenterology
; 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467382
4.
GDF5+ chondroprogenitors derived from human pluripotent stem cells preferentially form permanent chondrocytes.
Development
; 149(11)2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35451016
5.
Benchmark of embedding-based methods for accurate and transferable prediction of drug response.
Brief Bioinform
; 24(3)2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36961310
6.
Genetic overlap between Alzheimer's disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence.
Mol Psychiatry
; 2024 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38499654
7.
Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies.
Proc Natl Acad Sci U S A
; 119(16): e2117857119, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35412907
8.
DegronMD: Leveraging Evolutionary and Structural Features for Deciphering Protein-Targeted Degradation, Mutations, and Drug Response to Degrons.
Mol Biol Evol
; 40(12)2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37992195
9.
Identifying candidate genes and drug targets for Alzheimer's disease by an integrative network approach using genetic and brain region-specific proteomic data.
Hum Mol Genet
; 31(19): 3341-3354, 2022 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35640139
10.
Gene expression imputation and cell-type deconvolution in human brain with spatiotemporal precision and its implications for brain-related disorders.
Genome Res
; 31(1): 146-158, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33272935
11.
Innately expressed estrogen-related receptors in the skeletal muscle are indispensable for exercise fitness.
FASEB J
; 37(2): e22727, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36583689
12.
Montelukast as a repurposable additive drug for standard-efficacy multiple sclerosis treatment: Emulating clinical trials with retrospective administrative health claims data.
Mult Scler
; 30(6): 696-706, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38660773
13.
WebCSEA: web-based cell-type-specific enrichment analysis of genes.
Nucleic Acids Res
; 50(W1): W782-W790, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35610053
14.
Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome.
PLoS Genet
; 17(12): e1009971, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34965247
15.
Advances and challenges in Bioinformatics and Biomedical Engineering: IWBBIO 2020.
BMC Bioinformatics
; 24(Suppl 2): 361, 2023 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37853364
16.
Identification of microRNAs and gene regulatory networks in cleft lip common in humans and mice.
Hum Mol Genet
; 30(19): 1881-1893, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34104955
17.
A developmental stage-specific network approach for studying dynamic co-regulation of transcription factors and microRNAs during craniofacial development.
Development
; 147(24)2020 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33234712
18.
Deep4mC: systematic assessment and computational prediction for DNA N4-methylcytosine sites by deep learning.
Brief Bioinform
; 22(3)2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32578842
19.
Landscape of drug-resistance mutations in kinase regulatory hotspots.
Brief Bioinform
; 22(3)2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32510566
20.
Distinct effect of prenatal and postnatal brain expression across 20 brain disorders and anthropometric social traits: a systematic study of spatiotemporal modularity.
Brief Bioinform
; 22(6)2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34086851